Smallville Season 1 - Episode 15: Nicodemus
Clark (Tom Welling) must solve the riddle of the mysterious Nicodemus flower and Lex's (Michael Rosenbaum) shady involvement after it infects the residents of Smallville removing their inhibitions - Jonathan (John Schneider) becomes a couch potato, Lana (Kristin Kreuk) puts the moves on Clark as the town Lolita and Pete (Sam Jones III) tries to kill Lex - then puts them into a deadly coma.
Allison Mack, Eric Johnson and Annette O'Toole also star. James Marshall directed the episode; written by Greg Walker with teleplay by Michael Green.