Smallville Season 1 - Episode 3: Jitters
Clark (Tom Welling) and Lex (Michael Rosenbaum) team up to rescue Clark's high school class after a janitor (guest star Tony Todd) takes them hostage in LuthorCorp. He claims his deadly "jitters" were caused by a mysterious contaminant and threatens to kill everyone unless he is shown a secret sublevel - which Lionel Luthor (guest star John Glover, Batman & Robin) denies ever existed.
Kristin Kreuk, Eric Johnson, Sam Jones III, Allison Mack, Annette O'Toole and John Schneider also star. Michael Watkins directed the episode written by Cherie Bennett & Jeff Gottesfeld.